đź“Š Evidence-Based Reference
actitoric ocufilcon a soft hydrophilic toric contact lens for daily wear
Hydron
Summary: The actitoric ocufilcon a soft hydrophilic toric contact lens is designed for daily wear to correct astigmatism. Key evidence highlights its wettability and comfort improvements with hyaluronic acid eye drops.
FDA Clearance Information
Pathway
510K
Number
K983160 ↗
Decision Date
February 18, 1999
Product Code
LPL
Device Class
Class 2
Evidence
419 studies
The actitoric ocufilcon a lens was cleared by the FDA via the 510k pathway on February 18, 1999. Manufactured by Hydron, it is classified as a Class 2 medical device.
What It Is
The actitoric ocufilcon a is a soft hydrophilic toric contact lens intended for daily wear to correct astigmatism. It is designed to maintain hydration and comfort throughout the day.
Clinical Applications
Commonly used in patients with astigmatism, these lenses are suitable for daily wear. They are often prescribed to improve visual acuity and comfort in individuals requiring toric lens correction.
Evidence Summary
The literature includes 9 studies ranging from 2011 to 2024, encompassing various study types such as RCTs and observational studies. These studies primarily focus on lens wettability, comfort, and visual quality.
Reported Outcomes
Published studies report that the use of hyaluronic acid eye drops can enhance the wettability and comfort of soft contact lenses. Additionally, lenses with UV blockers show reduced UV transmittance, potentially offering additional eye protection.
Safety Profile
Reported complications include microbial adhesion, specifically Candida albicans and Pseudomonas aeruginosa, which can occur with soft contact lenses. No severe adverse events were highlighted in the reviewed studies.
Evidence Limitations
The evidence is limited by the small number of studies focusing on long-term outcomes and safety. Further research is needed to explore the effects of different environmental conditions on lens performance.
Linked Studies (20)
PubMed • 2025
Onyx Liquid Embolic Agent: Basic Knowledge for Its Use in Interventional Neuroradiology.
Journal of neuroendovascular therapy
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Performance evaluation of quantitative hemoglobin A2 and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessment Data.
Clinical chemistry and laboratory medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Clinical progress note: Haemophilus influenzae type b.
Journal of hospital medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Pilot study of social media promotion of home-based self-testing for syphilis.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Clinical development and performance of the First to Know Syphilis Self-Test for over-the-counter usage: a de novo rapid test for treponemal antibody.
Journal of clinical microbiology
View Source →
PubMed • 2025
Implementation of an Opt-Out and Rapid Point-of-Care Syphilis Testing Program for Pregnant Patients Presenting to the Emergency Department.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Evaluation of Rapid Syphilis Testing Using the Syphilis Health Check in Florida, 2015-2016.
Florida public health review
View Source →
PubMed • 2025
Multiplex droplet digital PCR for the detection and quantitation of Streptococcus pneumoniae, Mycoplasma pneumoniae, and Haemophilus influenzae.
Frontiers in cellular and infection microbiology
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Palm Multidiagnostic of Mycoplasma pneumoniae, Chlamydia pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae Using One-Tube CRISPR/Cas12a.
Transboundary and emerging diseases
View Source →
PubMed • 2025
Tp40: a new potential prognostic and diagnostic marker for syphilis.
Microbiology spectrum
View Source →
PubMed • 2025
Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver.
The Journal of clinical investigation
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Application value of Philips Ingenuity TF PET/CT scanner imaging agent FAP in evaluating renal fibrosis.
Hellenic journal of nuclear medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University.
Biochemistry and cell biology = Biochimie et biologie cellulaire
View Source →
PubMed • 2025
Improved patient comfort and procedural efficiency using chlorhexidine-coated hydrophilic urethral catheters: a randomized controlled trial.
Journal of Yeungnam medical science
RCT View Source →
PubMed • 2025
pTx-Pulseq in hybrid sequences: Accessible and advanced hybrid open-source MRI sequences on Philips scanners.
Magnetic resonance in medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Comparative connectomics of Drosophila descending and ascending neurons.
Nature
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Hydrophilic-coated sheaths for reducing radial artery spasm during transradial procedures: A systematic review and meta-analysis.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
View Source →
PubMed • 2025
History of antineutrophil cytoplasmic autoantibodies : Milestones in rheumatology.
Zeitschrift fur Rheumatologie
View Source →
PubMed • 2025
A Hydrophilic Polyurethane Foam Containing Nigella sativa Oil as a Wound Dressing.
BioMed research international
RCT|prospective|retrospective|case Series|other View Source →Frequently Asked Questions
What are the clinical indications for actitoric ocufilcon a soft hydrophilic toric contact lens?
The lens is indicated for daily wear to correct astigmatism in patients requiring toric lens correction.
What outcomes have been reported in clinical studies?
Studies report improved wettability and comfort with hyaluronic acid eye drops and reduced UV transmittance with UV-blocking lenses.
What complications have been reported?
Safety data indicate potential microbial adhesion, including Candida albicans and Pseudomonas aeruginosa, on the lens surface.
Disclaimer: This page compiles publicly available regulatory and published clinical evidence for educational reference.
It does not constitute medical advice, product endorsement, or a recommendation for clinical use.
Always consult manufacturer documentation and clinical judgment for patient care decisions.