đź“Š Evidence-Based Reference
methafilcon a soft hydrophilic contact lenses frequency 55 frequency 55 uv to be marketed yr 2000 frequency 55 asp
Coopervision
Summary: Methafilcon A soft hydrophilic contact lenses by Coopervision are primarily used for vision correction. Key evidence includes studies on lens performance and bacterial adhesion.
FDA Clearance Information
Pathway
510K
Number
K993252 ↗
Decision Date
November 24, 1999
Product Code
MVN
Device Class
Class 2
Evidence
419 studies
The methafilcon A soft contact lenses were cleared through the FDA 510(k) pathway on November 24, 1999. Manufactured by Coopervision, they are classified as Class 2 medical devices.
What It Is
Methafilcon A soft contact lenses are hydrophilic lenses designed for vision correction. They are intended for daily wear and offer UV protection, providing comfort and clarity for users.
Clinical Applications
These lenses are commonly used in patients requiring vision correction for conditions such as myopia or hyperopia. They are suitable for daily wear and provide UV protection, making them practical for regular use.
Evidence Summary
The available literature includes three studies ranging from 2012 to 2019. Study types include randomized controlled trials and in vitro analyses, focusing on lens performance and bacterial interactions.
Reported Outcomes
Published studies report that methafilcon A lenses perform comparably to other large diameter lenses in terms of clinical performance. In vitro studies indicate that bacterial biofilms can inhibit therapeutic diffusion across lenses.
Safety Profile
Reported complications include the potential for bacterial adhesion, as demonstrated in studies involving Staphylococcus aureus and Pseudomonas aeruginosa. No adverse events were directly linked to lens wear in the reviewed studies.
Evidence Limitations
The evidence is limited by the small number of studies and a lack of large-scale clinical trials. Further research is needed to explore long-term safety and efficacy, particularly in diverse patient populations.
Linked Studies (20)
PubMed • 2025
Onyx Liquid Embolic Agent: Basic Knowledge for Its Use in Interventional Neuroradiology.
Journal of neuroendovascular therapy
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Performance evaluation of quantitative hemoglobin A2 and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessment Data.
Clinical chemistry and laboratory medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Clinical progress note: Haemophilus influenzae type b.
Journal of hospital medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Pilot study of social media promotion of home-based self-testing for syphilis.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Clinical development and performance of the First to Know Syphilis Self-Test for over-the-counter usage: a de novo rapid test for treponemal antibody.
Journal of clinical microbiology
View Source →
PubMed • 2025
Implementation of an Opt-Out and Rapid Point-of-Care Syphilis Testing Program for Pregnant Patients Presenting to the Emergency Department.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Evaluation of Rapid Syphilis Testing Using the Syphilis Health Check in Florida, 2015-2016.
Florida public health review
View Source →
PubMed • 2025
Multiplex droplet digital PCR for the detection and quantitation of Streptococcus pneumoniae, Mycoplasma pneumoniae, and Haemophilus influenzae.
Frontiers in cellular and infection microbiology
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Palm Multidiagnostic of Mycoplasma pneumoniae, Chlamydia pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae Using One-Tube CRISPR/Cas12a.
Transboundary and emerging diseases
View Source →
PubMed • 2025
Tp40: a new potential prognostic and diagnostic marker for syphilis.
Microbiology spectrum
View Source →
PubMed • 2025
Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver.
The Journal of clinical investigation
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Application value of Philips Ingenuity TF PET/CT scanner imaging agent FAP in evaluating renal fibrosis.
Hellenic journal of nuclear medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University.
Biochemistry and cell biology = Biochimie et biologie cellulaire
View Source →
PubMed • 2025
Improved patient comfort and procedural efficiency using chlorhexidine-coated hydrophilic urethral catheters: a randomized controlled trial.
Journal of Yeungnam medical science
RCT View Source →
PubMed • 2025
pTx-Pulseq in hybrid sequences: Accessible and advanced hybrid open-source MRI sequences on Philips scanners.
Magnetic resonance in medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Comparative connectomics of Drosophila descending and ascending neurons.
Nature
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Hydrophilic-coated sheaths for reducing radial artery spasm during transradial procedures: A systematic review and meta-analysis.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
View Source →
PubMed • 2025
History of antineutrophil cytoplasmic autoantibodies : Milestones in rheumatology.
Zeitschrift fur Rheumatologie
View Source →
PubMed • 2025
A Hydrophilic Polyurethane Foam Containing Nigella sativa Oil as a Wound Dressing.
BioMed research international
RCT|prospective|retrospective|case Series|other View Source →Frequently Asked Questions
What are the clinical indications for methafilcon A soft contact lenses?
Methafilcon A lenses are indicated for vision correction in conditions like myopia and hyperopia, suitable for daily wear.
What outcomes have been reported in clinical studies?
Studies report comparable performance to other lenses and note bacterial biofilm impact on therapeutic diffusion.
What complications have been reported?
Safety data indicate potential bacterial adhesion, but no direct adverse events from lens wear were reported.
Disclaimer: This page compiles publicly available regulatory and published clinical evidence for educational reference.
It does not constitute medical advice, product endorsement, or a recommendation for clinical use.
Always consult manufacturer documentation and clinical judgment for patient care decisions.