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philips pls9w 12 2p uvb
Philips Lighting
Summary: The Philips PLS9W 12 2P UVB is a UVB phototherapy device primarily used for treating psoriasis. Key evidence indicates its efficacy in reducing PASI scores with near erythemogenic doses.
FDA Clearance Information
Pathway
510K
Number
K021514 ↗
Decision Date
May 16, 2002
Product Code
FTC
Device Class
Class 2
Evidence
419 studies
The Philips PLS9W 12 2P UVB was cleared by the FDA through the 510(k) pathway on May 16, 2002. It is manufactured by Philips Lighting and classified as a Class 2 device.
What It Is
The Philips PLS9W 12 2P UVB is a narrow-band ultraviolet B phototherapy device designed to deliver specific UVB wavelengths for therapeutic purposes. It is intended for use in dermatological conditions such as psoriasis.
Clinical Applications
This device is commonly used in clinical settings for the treatment of psoriasis, leveraging its ability to deliver targeted UVB radiation to reduce skin lesions and inflammation.
Evidence Summary
The available literature includes two studies, with one being a randomized controlled trial from 1998 and another study from 1994. These studies explore the efficacy and safety of UVB phototherapy.
Reported Outcomes
Published studies report that near erythemogenic doses of UVB therapy significantly reduce PASI scores in psoriasis patients, with a median total of 12 treatments needed for satisfactory response. Far erythemogenic doses were less effective, requiring more treatments and resulting in lower PASI score improvements.
Safety Profile
Reported complications include no specific adverse events noted in the provided studies. However, general UVB therapy risks such as skin erythema and potential long-term carcinogenic effects are known.
Evidence Limitations
The evidence is limited by the small sample size and the lack of recent studies. Further research is needed to confirm long-term safety and efficacy, as well as to explore the device's use in other dermatological conditions.
Linked Studies (20)
PubMed • 2025
Onyx Liquid Embolic Agent: Basic Knowledge for Its Use in Interventional Neuroradiology.
Journal of neuroendovascular therapy
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Performance evaluation of quantitative hemoglobin A2 and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessment Data.
Clinical chemistry and laboratory medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Clinical progress note: Haemophilus influenzae type b.
Journal of hospital medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Pilot study of social media promotion of home-based self-testing for syphilis.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Clinical development and performance of the First to Know Syphilis Self-Test for over-the-counter usage: a de novo rapid test for treponemal antibody.
Journal of clinical microbiology
View Source →
PubMed • 2025
Implementation of an Opt-Out and Rapid Point-of-Care Syphilis Testing Program for Pregnant Patients Presenting to the Emergency Department.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Evaluation of Rapid Syphilis Testing Using the Syphilis Health Check in Florida, 2015-2016.
Florida public health review
View Source →
PubMed • 2025
Multiplex droplet digital PCR for the detection and quantitation of Streptococcus pneumoniae, Mycoplasma pneumoniae, and Haemophilus influenzae.
Frontiers in cellular and infection microbiology
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Palm Multidiagnostic of Mycoplasma pneumoniae, Chlamydia pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae Using One-Tube CRISPR/Cas12a.
Transboundary and emerging diseases
View Source →
PubMed • 2025
Tp40: a new potential prognostic and diagnostic marker for syphilis.
Microbiology spectrum
View Source →
PubMed • 2025
Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver.
The Journal of clinical investigation
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Application value of Philips Ingenuity TF PET/CT scanner imaging agent FAP in evaluating renal fibrosis.
Hellenic journal of nuclear medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University.
Biochemistry and cell biology = Biochimie et biologie cellulaire
View Source →
PubMed • 2025
Improved patient comfort and procedural efficiency using chlorhexidine-coated hydrophilic urethral catheters: a randomized controlled trial.
Journal of Yeungnam medical science
RCT View Source →
PubMed • 2025
pTx-Pulseq in hybrid sequences: Accessible and advanced hybrid open-source MRI sequences on Philips scanners.
Magnetic resonance in medicine
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Comparative connectomics of Drosophila descending and ascending neurons.
Nature
RCT|prospective|retrospective|case Series|other View Source →
PubMed • 2025
Hydrophilic-coated sheaths for reducing radial artery spasm during transradial procedures: A systematic review and meta-analysis.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
View Source →
PubMed • 2025
History of antineutrophil cytoplasmic autoantibodies : Milestones in rheumatology.
Zeitschrift fur Rheumatologie
View Source →
PubMed • 2025
A Hydrophilic Polyurethane Foam Containing Nigella sativa Oil as a Wound Dressing.
BioMed research international
RCT|prospective|retrospective|case Series|other View Source →Frequently Asked Questions
What are the clinical indications for Philips PLS9W 12 2P UVB?
The device is indicated for the treatment of psoriasis, utilizing narrow-band UVB phototherapy to reduce skin lesions.
What outcomes have been reported in clinical studies?
Clinical studies have reported significant reductions in PASI scores with near erythemogenic doses of UVB therapy, indicating effective treatment of psoriasis.
What complications have been reported?
No specific complications were reported in the provided studies, though general risks of UVB therapy include skin erythema and potential carcinogenic effects.
Disclaimer: This page compiles publicly available regulatory and published clinical evidence for educational reference.
It does not constitute medical advice, product endorsement, or a recommendation for clinical use.
Always consult manufacturer documentation and clinical judgment for patient care decisions.