- like a stiff “canvas sack” around the bacterial cell.
- maintains cell structure.
- is a permeability barrier to large molecules (like lysozyme) and hydrophobic molecules; also provides protection from adverse environments like the GI tract.
- has an asymmetric bilayer structure: inner leaflet similar to other phospholipid membranes, but outer leaflet contains LPS.
- contains a group of transmembrane proteins, porins, that form pores allowing diffusion of small hydrophilic molecules.
- is involved in signal transduction, e.g. quorum sensing: communication among bacteria.
- can be disrupted by antibiotics, like polymyxin.
Outer Membrane of Gram-negative Cells
Still have questions?
Ask our vascular team — plain answers, no cost, no obligation. If it's about your own care, we'll connect you with a specialist.
Having fever, spreading redness, chest pain, or trouble breathing? Contact your doctor or seek emergency care now — don’t wait on a reply here.
Attorney reviewing a case? Request a board-certified medical expert →