Portal vein embolization with sotradecol technique and dictation

PROCEDURE: 

  1. Main portal venography
  2. Right anterior portal vein embolization
  3. Right posterior portal vein embolization
  4. Postembolization main portal venography

 

DATE OF PROCEDURE:    

INDICATION:     old    ,    .    

OPERATORS: (Attending),  (Fellow)

COMPARISON: None

MEDICATIONS: None. Sedation medications were administered by the anesthesiology team as the patient was under general anesthesia.

CONTRAST: 0 ml of nonionic contrast 

FLUOROSCOPY TIME: 18.6 minutes

ACCESS SITE: Right abdominal percutaneous access x2

 

COMPLICATIONS: None

 

TECHNIQUE: The risks, benefits, and alternatives to the procedure and sedation were explained to the patient, and written informed consent obtained. A timeout was performed.  The patient was placed in a slight right anterior oblique position on the angiography table and the right groin was was prepped and draped in sterile fashion. A timeout was performed.

The abdomen was evaluated by ultrasound. An appropriate entry site to access the right posterior portal vein was chosen and anesthetized with 1% bupivacaine. Using ultrasound guidance, a right posterior portal vein branch was accessed with a 22-gauge Chiba needle. Needle entry was documented. There stylet was removed and intravascular position confirmed by contrast injection under fluoroscopy. A 0.018″ guidewire was inserted through the needle into the main portal vein. A small dermatotomy was made around the needle. The needle was replaced with a transitional 6 F Aprima dilator set. The inner dilator and 0.018″ guidewire were removed. The outer transitional dilator was replaced over an Amplatz guidewire for a 7 F, 25 cm vascular sheath. 

The abdomen was evaluated by ultrasound. An appropriate entry site to access the right anterior portal vein was chosen and anesthetized with 1% bupivacaine. Using ultrasound guidance, a right anterior portal vein branch was accessed with a 22-gauge Chiba needle. Needle entry was documented. The stylet was removed and intravascular position confirmed by contrast injection under fluoroscopy. A 0.018″ guidewire was inserted through the needle into the main portal vein. A small dermatotomy was made around the needle. The needle was replaced with a transitional 6 F Aprima dilator set. The inner dilator and 0.018″ guidewire were removed. The outer transitional dilator was replaced over an Amplatz guidewire for a 7 F, 25 cm vascular sheath. 

A straight flush catheter was placed over the right anterior portal vein guidewire into the main portal vein. Digital subtraction venography was performed using the power injector. The straight flush catheter was removed.

6 F, 13 mm Python balloons were placed over the guidewires. Position of the sheaths and balloons was adjusted and the balloons was inflated in appropriate position to occlude the origin of the anterior and posterior right portal vein. Digital subtraction venography was performed through both sheaths. Digital subtraction venography was then performed through one of the balloons.

Approximately 15 mL of a 3:2:1 air:Sotradecol:Lipiodol foam mixture was injected into each sheath under close fluoroscopic evaluation of the main and left portal veins to ensure no leakage beyond the balloons.

After approximately 15 minutes, an additional 7 to 8 mL of the foam was injected into each sheath.

After an additional 25 minutes, the balloons were deflated and removed. A straight flush catheter was again placed over one of the wires and used to obtain digital subtraction main portal venography.

The wires were removed. The sheaths were cut and the parenchymal tract was embolized with Gelfoam pledgets. The sheaths were completely removed. Sterile dressings were applied.

The patient tolerated the procedure well and left the angiography suite in stable condition without any immediate postprocedural complications. 

 

FINDINGS: 

  1. Preembolization portal venography demonstrates a trifurcation of the portal system into right anterior, right posterior, and left portal vein branches. Percutaneous access is established in the right anterior and right posterior branches.
  2. Sotradecol foam infusion shows appropriate filling of the right anterior and right posterior portal systems. No leakage is observed into the main or left portal veins.
  3. Post embolization portal venogram demonstrates complete embolization of the right anterior and posterior portal venous vasculature without contrast filling.

 

IMPRESSION: Successful right anterior and posterior portal vein embolization with Sotradecol foam.

Frequently Asked Questions

What is portal vein embolization and why is it done?

Portal vein embolization (PVE) is a medical procedure used to block blood flow to certain parts of the liver. It's typically done to encourage the growth of the liver remnant before major liver surgery, such as a resection, which removes part of the liver. By embolizing the portal vein, the liver segments not being removed can grow larger, making surgery safer and reducing the risk of liver failure.

How is portal vein embolization performed using the Sotradecol technique?

In the Sotradecol technique for PVE, a mixture of Sotradecol, air, and Lipiodol is used to create a foam that occludes the targeted portal veins. The procedure involves accessing the portal vein branches via a needle, confirmed with ultrasound and fluoroscopy. Balloons are used to block blood flow, and the foam is injected to fill the portal vein branches, ensuring no leakage occurs. This technique effectively blocks blood flow to encourage liver growth elsewhere.

What are the potential complications of portal vein embolization?

Portal vein embolization is generally safe, but like any medical procedure, it carries potential risks. Complications can include bleeding, infection, or adverse reactions to the embolic material. However, in the described procedure, no immediate complications were observed, and the patient tolerated the procedure well. Patients are closely monitored post-procedure to quickly address any issues that may arise.

Why is ultrasound guidance used during portal vein embolization?

Ultrasound guidance is crucial during portal vein embolization for accurately locating the portal vein branches and ensuring precise needle placement. This imaging technique allows the physician to visualize the internal structures in real-time, reducing the risk of injury to surrounding tissues and ensuring that the embolic agents are delivered to the correct location.

What is Sotradecol and how does it work in embolization?

Sotradecol, or sodium tetradecyl sulfate, is a sclerosing agent used in medical procedures to irritate and close off veins. In the context of portal vein embolization, it's mixed with air and Lipiodol to form a foam that blocks blood flow in targeted veins, effectively redirecting blood flow and promoting growth in other parts of the liver. This process helps in preparing the liver for major surgical interventions.

What is the role of digital subtraction venography in this procedure?

Digital subtraction venography is an imaging technique used during portal vein embolization to visualize blood flow within the veins. It involves injecting a contrast agent and capturing images that highlight the veins by subtracting background structures. This allows physicians to confirm the placement of embolic materials and ensure that the targeted veins are adequately blocked without leakage.

Can portal vein embolization be done under local anesthesia?

Portal vein embolization is often performed under general anesthesia to ensure patient comfort and immobility during the procedure. However, some cases might allow for local anesthesia if the patient's condition permits. The procedure involves accessing veins deep within the abdomen, so patient immobility is crucial for precision, which is more effectively achieved with general anesthesia.

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