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Largan Hioxifilcon a Daily Wear Soft Hydrophilic Contact Lens Largan Hioxifilcon a Daily Wear Soft Hydrophilic Contact Lens for Astigmatism Largan Hioxifilcon a Daily Wear Soft Hydrophilic Contact Lens for Presbyopia
Largan Medical
Summary: The Largan Hioxifilcon A is a daily wear soft hydrophilic contact lens designed for general vision correction, astigmatism, and presbyopia. It is used by optometrists and ophthalmologists for patients needing vision correction.
FDA Clearance Information
Pathway ?
510(k)
Number ?
K170286 ↗
Decision Date ?
September 18, 2017
Product Code ?
LPL
Device Class ?
Class 2
Evidence ?
419 studies
The Largan Hioxifilcon A contact lens was cleared through the FDA 510k pathway on September 18, 2017. Manufactured by Largan Medical, it is classified as a Class 2 medical device.
What It Is
The Largan Hioxifilcon A is a soft hydrophilic contact lens intended for daily wear. It is made from a water-containing polymer that allows oxygen to reach the cornea, enhancing comfort and reducing dryness. The lens is available in versions for general vision correction, astigmatism, and presbyopia, addressing a wide range of refractive errors.
FDA-Cleared Indications
- Daily-wear correction of myopia and hyperopia with the spherical lens design.
- Daily-wear correction of astigmatism with the toric lens design.
- Daily-wear correction of presbyopia with the multifocal lens design.
Clinical Applications
- Correction of nearsightedness in patients prescribed the spherical lens design.
- Correction of farsightedness in patients prescribed the spherical lens design.
- Correction of astigmatism with the toric lens design.
- Correction of age-related presbyopia with the multifocal lens design.
- Daily, daytime vision correction as prescribed and fitted by an eye-care professional.
Practical Considerations
- The lens must be properly fitted by an optometrist or ophthalmologist, including selection of the prescription, base curve, diameter, and lens design.
- Daily-wear lenses should be removed before sleeping unless the specific product labeling and eye-care professional allow otherwise.
- Use only the recommended contact-lens cleaning and disinfecting system; do not use tap water or saliva to clean or store the lens.
- Patients with active eye infection, significant eye inflammation, or conditions that interfere with lens wear may need to avoid contact lenses until evaluated by an eye-care professional.
- Contact lenses are not implanted devices and have no MRI-specific restriction; they should be removed if directed for an eye examination or procedure.
Linked Studies (20)
PubMed • 2025
Onyx Liquid Embolic Agent: Basic Knowledge for Its Use in Interventional Neuroradiology.
Journal of neuroendovascular therapy
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Performance evaluation of quantitative hemoglobin A2 and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessment Data.
Clinical chemistry and laboratory medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Clinical progress note: Haemophilus influenzae type b.
Journal of hospital medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Pilot study of social media promotion of home-based self-testing for syphilis.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Clinical development and performance of the First to Know Syphilis Self-Test for over-the-counter usage: a de novo rapid test for treponemal antibody.
Journal of clinical microbiology
View Source →PubMed • 2025
Implementation of an Opt-Out and Rapid Point-of-Care Syphilis Testing Program for Pregnant Patients Presenting to the Emergency Department.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Evaluation of Rapid Syphilis Testing Using the Syphilis Health Check in Florida, 2015-2016.
Florida public health review
View Source →PubMed • 2025
Multiplex droplet digital PCR for the detection and quantitation of Streptococcus pneumoniae, Mycoplasma pneumoniae, and Haemophilus influenzae.
Frontiers in cellular and infection microbiology
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Palm Multidiagnostic of Mycoplasma pneumoniae, Chlamydia pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae Using One-Tube CRISPR/Cas12a.
Transboundary and emerging diseases
View Source →PubMed • 2025
Tp40: a new potential prognostic and diagnostic marker for syphilis.
Microbiology spectrum
View Source →PubMed • 2025
Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver.
The Journal of clinical investigation
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Application value of Philips Ingenuity TF PET/CT scanner imaging agent FAP in evaluating renal fibrosis.
Hellenic journal of nuclear medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University.
Biochemistry and cell biology = Biochimie et biologie cellulaire
View Source →PubMed • 2025
Improved patient comfort and procedural efficiency using chlorhexidine-coated hydrophilic urethral catheters: a randomized controlled trial.
Journal of Yeungnam medical science
RCT View Source →PubMed • 2025
pTx-Pulseq in hybrid sequences: Accessible and advanced hybrid open-source MRI sequences on Philips scanners.
Magnetic resonance in medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Comparative connectomics of Drosophila descending and ascending neurons.
Nature
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Hydrophilic-coated sheaths for reducing radial artery spasm during transradial procedures: A systematic review and meta-analysis.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
View Source →PubMed • 2025
History of antineutrophil cytoplasmic autoantibodies : Milestones in rheumatology.
Zeitschrift fur Rheumatologie
View Source →PubMed • 2025
A Hydrophilic Polyurethane Foam Containing Nigella sativa Oil as a Wound Dressing.
BioMed research international
RCT|prospective|retrospective|case Series|other View Source →Frequently Asked Questions
What is Largan Hioxifilcon A contact lens used for?
It is used for correcting vision in patients with myopia, hyperopia, astigmatism, and presbyopia.
What specialties typically use this device?
Optometrists and ophthalmologists typically use these lenses in their practices.
What are the FDA-cleared indications?
The lenses are indicated for daily wear to correct refractive errors such as nearsightedness, farsightedness, astigmatism, and presbyopia.
Disclaimer: This page compiles publicly available regulatory and published clinical evidence for educational reference.
It does not constitute medical advice, product endorsement, or a recommendation for clinical use.
Always consult manufacturer documentation and clinical judgment for patient care decisions.