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Canalizer Hydrophilic Guide Wire
Medical Device Technologies
Summary: The canalizer hydrophilic guide wire is a medical device used to navigate through blood vessels during procedures like embolization. It is primarily used by interventional radiologists and vascular surgeons.
FDA Clearance Information
Pathway ?
510(k)
Number ?
K050873 ↗
Decision Date ?
May 26, 2005
Product Code ?
DQX Wire, Guide, Catheter
Device Class ?
Class 2
Evidence ?
419 studies
The canalizer hydrophilic guide wire was cleared through the FDA 510(k) pathway on May 26, 2005. Manufactured by Medical Device Technologies, it is classified as a Class 2 device under product code DQX.
What It Is
The canalizer hydrophilic guide wire is a flexible wire with a hydrophilic coating that reduces friction, allowing it to glide smoothly through blood vessels. This device is crucial in minimally invasive procedures, aiding in the placement of catheters and other devices within the vascular system. Its design helps clinicians navigate complex vascular pathways with precision.
FDA-Cleared Indications
- Used to facilitate the placement and positioning of catheters within blood vessels during intravascular procedures.
- Used for vascular navigation when access to or treatment of a selected vascular area is required.
- Intended for use with compatible catheters and endovascular devices in procedures performed under imaging guidance.
Clinical Applications
- Guiding catheters through blood vessels during diagnostic or therapeutic endovascular procedures.
- Facilitating catheter placement for embolization procedures when a catheter must be navigated to a selected vascular territory.
- Supporting catheter positioning during angioplasty and other intravascular interventions, when consistent with the device labeling.
- Navigating tortuous or branching vascular anatomy to obtain more selective catheter access.
Practical Considerations
- Available guide wires may differ in diameter, length, tip shape, stiffness and coating; the selected wire must match the catheter and the target anatomy.
- The hydrophilic coating requires activation with sterile fluid according to the instructions for use. The wire should not be advanced or withdrawn against significant resistance.
- Use sterile technique and fluoroscopic or other appropriate imaging guidance. Excessive force, deep advancement or wire entrapment can cause vessel dissection, perforation or other injury.
- MRI safety depends on the exact device configuration and labeling. Do not assume the wire is MR safe or MR conditional without confirming the manufacturer’s instructions for use.
- Potential contraindications and warnings include inability to obtain safe vascular access, uncorrected bleeding risk, severe vessel disease or anatomy that makes wire passage unsafe. The treating clinician should review the product labeling and patient-specific risks.
Linked Studies (20)
PubMed • 2025
Onyx Liquid Embolic Agent: Basic Knowledge for Its Use in Interventional Neuroradiology.
Journal of neuroendovascular therapy
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Performance evaluation of quantitative hemoglobin A2 and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessment Data.
Clinical chemistry and laboratory medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Clinical progress note: Haemophilus influenzae type b.
Journal of hospital medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Pilot study of social media promotion of home-based self-testing for syphilis.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Clinical development and performance of the First to Know Syphilis Self-Test for over-the-counter usage: a de novo rapid test for treponemal antibody.
Journal of clinical microbiology
View Source →PubMed • 2025
Implementation of an Opt-Out and Rapid Point-of-Care Syphilis Testing Program for Pregnant Patients Presenting to the Emergency Department.
Sexually transmitted diseases
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Evaluation of Rapid Syphilis Testing Using the Syphilis Health Check in Florida, 2015-2016.
Florida public health review
View Source →PubMed • 2025
Multiplex droplet digital PCR for the detection and quantitation of Streptococcus pneumoniae, Mycoplasma pneumoniae, and Haemophilus influenzae.
Frontiers in cellular and infection microbiology
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Palm Multidiagnostic of Mycoplasma pneumoniae, Chlamydia pneumoniae, Haemophilus influenzae, and Streptococcus pneumoniae Using One-Tube CRISPR/Cas12a.
Transboundary and emerging diseases
View Source →PubMed • 2025
Tp40: a new potential prognostic and diagnostic marker for syphilis.
Microbiology spectrum
View Source →PubMed • 2025
Serotonin sets up neutrophil extracellular traps to promote neuroendocrine prostate cancer metastasis in the liver.
The Journal of clinical investigation
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Application value of Philips Ingenuity TF PET/CT scanner imaging agent FAP in evaluating renal fibrosis.
Hellenic journal of nuclear medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University.
Biochemistry and cell biology = Biochimie et biologie cellulaire
View Source →PubMed • 2025
Improved patient comfort and procedural efficiency using chlorhexidine-coated hydrophilic urethral catheters: a randomized controlled trial.
Journal of Yeungnam medical science
RCT View Source →PubMed • 2025
pTx-Pulseq in hybrid sequences: Accessible and advanced hybrid open-source MRI sequences on Philips scanners.
Magnetic resonance in medicine
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Comparative connectomics of Drosophila descending and ascending neurons.
Nature
RCT|prospective|retrospective|case Series|other View Source →PubMed • 2025
Hydrophilic-coated sheaths for reducing radial artery spasm during transradial procedures: A systematic review and meta-analysis.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
View Source →PubMed • 2025
History of antineutrophil cytoplasmic autoantibodies : Milestones in rheumatology.
Zeitschrift fur Rheumatologie
View Source →PubMed • 2025
A Hydrophilic Polyurethane Foam Containing Nigella sativa Oil as a Wound Dressing.
BioMed research international
RCT|prospective|retrospective|case Series|other View Source →Frequently Asked Questions
What is the canalizer hydrophilic guide wire used for?
It is used for navigating blood vessels during procedures like embolization and angioplasty.
What specialties typically use this device?
Interventional radiologists and vascular surgeons commonly use this device.
What are the FDA-cleared indications?
It is indicated for use in procedures requiring vascular navigation, such as embolization with liquid agents.
Disclaimer: This page compiles publicly available regulatory and published clinical evidence for educational reference.
It does not constitute medical advice, product endorsement, or a recommendation for clinical use.
Always consult manufacturer documentation and clinical judgment for patient care decisions.