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peripherally inserted central venous catheter
Catheter Technology
Summary: A peripherally inserted central venous catheter (PICC) is used for prolonged intravenous therapy. Key evidence highlights its efficacy in outpatient antibiotic treatment and its safety profile in various clinical settings.
FDA Clearance Information
Pathway
510K
Number
K871080 ↗
Decision Date
August 12, 1987
Product Code
DQY
Device Class
Class 2
Evidence
0 studies
The peripherally inserted central venous catheter by Catheter Technology was cleared by the FDA via the 510k pathway on August 12, 1987. It is classified as a Class 2 device.
What It Is
A peripherally inserted central venous catheter (PICC) is a long, thin tube inserted through a peripheral vein and advanced to a central vein. It is intended for prolonged intravenous therapy, including antibiotics, chemotherapy, and parenteral nutrition.
Clinical Applications
PICCs are commonly used in patients requiring long-term intravenous therapy, such as those with infections, hematological malignancies, or undergoing chemotherapy. They provide reliable venous access while minimizing repeated needle sticks.
Evidence Summary
The literature includes 14 studies, encompassing retrospective analyses and case series, published between 2023 and 2024. These studies evaluate the efficacy and safety of PICCs in various patient populations.
Reported Outcomes
Published studies report that PICCs are effective in outpatient intravenous antibiotic therapy for spinal infections, with a high absence of spondylodiscitis (99%) and no catheter-related complications. In pediatric acute leukemia, PICCs are increasingly used for long-term access, though data remain limited.
Safety Profile
Reported complications include infections, thrombosis, and mechanical issues, particularly in patients with hematological malignancies. However, one study noted no catheter-related complications in outpatient antibiotic therapy for spinal infections.
Evidence Limitations
Evidence gaps include limited data on long-term outcomes in pediatric populations and the need for more prospective studies to better understand complication rates. Further research is needed to optimize PICC use in diverse clinical settings.
Frequently Asked Questions
What are the clinical indications for peripherally inserted central venous catheter?
Indications include prolonged intravenous therapy for infections, chemotherapy, and parenteral nutrition.
What outcomes have been reported in clinical studies?
Studies report high efficacy in outpatient antibiotic therapy for spinal infections and successful use in pediatric leukemia.
What complications have been reported?
Complications include infections, thrombosis, and mechanical issues, though some studies report no complications in specific settings.
Disclaimer: This page compiles publicly available regulatory and published clinical evidence for educational reference.
It does not constitute medical advice, product endorsement, or a recommendation for clinical use.
Always consult manufacturer documentation and clinical judgment for patient care decisions.