What is the most frequently reported central nervous system (CNS) fungal infection, and what are its key imaging characteristics?

Cryptococcosis is the most frequently reported CNS fungal infection. Key diagnostic features on MRI include gelatinous pseudocysts in the basal ganglia and periventricular regions, often appearing as hyperintense lesions on T2-weighted images. Clinically, it is important to consider cryptococcosis in immunocompromised patients, particularly those with HIV/AIDS. Common pitfalls include mistaking these lesions for other causes of meningitis or neoplastic processes.