What are the typical MRI myelination patterns observed in the brain by 3 months of age, specifically on T1-weighted images?

By 3 months of age, myelination on T1-weighted MRI typically shows high signal intensity in the anterior limb of the internal capsule and cerebellar white matter. Key diagnostic features include the progression of myelination from central to peripheral and from caudal to rostral regions. Clinically, recognizing these patterns helps differentiate normal developmental myelination from pathological conditions. A common pitfall is mistaking delayed myelination for hypoxic-ischemic injury, which requires careful correlation with clinical history and other imaging findings.