| Property | Prokaryotic Bacterial Cells | Eukaryotic Human Cells |
| DNA within a nuclear membrane | No | Yes |
| Number of chromosomes | 1 | More than 1 |
| Mechanism of Replication | Binary Fission | Mitosis |
| Presence of organelles, e.g. Golgi, mitochondria, lysosomes, endoplasmic reticulum | No | Yes |
| Size of Ribosome | 70S | 80S |
| Site of respiratory electron transport | Cytoplasmic membrane | Mitochondria |
| Cell wall containing peptidoglycan | Yes (except Mycoplasma) | No |
| Cell membrane containing sterols | No (except Mycoplasma) | Yes |